Scarlet fever (strawberry tongue, pharyngitis, diffuse rash that spares the face) – SpeA, C 2. Streptococcal pyrogenic exotoxin (Spe) 1.
*Eriseplas (very superficial cellulitis infection – erythema of the skin - with well demarcated borders) Cellulitis & eriseplas pyogenic infections. Impetigo – honey crusted (also in staph aureus) 2. Encapsulated – Hyaluronic acid capsule therefore not immunogenic.Strep: Grow on a single axis and form long chains/pairs - GRAM POSITIVE, BACITRACIN SENSITIVE Strep Pyogenes Strep Pyogenes – Group A Strep “The Pie Genies’ Bakery” BOTH ARE CATALASE POSITIVE Gram Positive BOTH ARE UREASE POSITIVE COAGULASE NEGATIVE Common cause of UTIs in sexually active females. Makes copious amounts of biofilms (a mess of polysaccharides, helps it stick to surfaces and acts as coating that protects it from antibiotics and immune cells) therefore resistant to many antibiotics. MCC of endocarditis affecting artificially implanted heart valves.infects artificial joints and catheters.Staph Epidermidis & Saprophyticus “Beauty and the Plumber” If methicillin sensitive than use appropriate penicllin – nafcillin. MRSA - resistance by altering PBP – use vancomycin. More associated with vomitting than diarrhea – found in meats and custards and mayonnaise. Staph food poisoning – rapid onset, preformed toxin.Toxic Shock Syndrome – superantigen toxic shock syndrome toxin (TSST)– non specific binding (MHC II and TCR), cytokine storm – TAMPON.Scalded Skin Syndrome – exfoliatin toxin – a protease.Rapid onset of acute bacterial endocarditis in IV drug users – right sided heart valves (tricuspid valve). Most common cause of septic arthritis, cellulitis, impetigo, carbuncles, pharuncles, abscesses. Causes pneumonia – patchy infiltrates on xray, icosahedron shaped lamps (capsules) post-viral bacterial pneumonia. Protein A – main virulence factor, component of cell wall and binds Fc portion of Ig and prevents opsonization. Plate on mannitol salt agar – can ferment and turn agar yellow. Coagulase positive (converts fibrinogen to fibrin). Gram positive (take up crystal violet stain in their thick cell walls). Suggested printing template (6 slides per page): 1īundle of grapes.